Restoring Menin protein and D serine amino acid reverses cognitive decline in mice

Science Daily Exercise reported that scientists discovered declining levels of a protein called Menin may drive the aging process. Restoring Menin levels in older mice reversed several age-related changes within 30 days. The researchers also found that supplementing with the amino acid D-serine improved memory and learning in the animals. [1]

The findings suggest that some physical and mental changes associated with aging may stem from the loss of a single protein inside the brain. Restoring Menin protein in older mice specifically improved brain function and helped combat age-related cognitive decline. [1]

Scientific investigation into biological aging and methods to delay brain aging has a long history, as documented in historical timelines of senescence research. Recent studies continue to focus on targeting specific proteins to reverse age-related deterioration. [2]

This discovery builds on earlier research into protein manipulation to combat aging. As FTMQ Health reported earlier, researchers previously found that blocking a different age-related protein helped regrow damaged knee cartilage in older mice and human tissue samples. [3]

The latest study on Menin and D-serine offers a potential new therapeutic approach to address age-related memory loss. Further research will be required to determine whether these laboratory results in mice can be safely replicated in humans. [1]