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Merck and Moderna advance personalized mRNA cancer vaccine clinical trials

Pharmaceutical companies Merck and Moderna are pairing personalized mRNA vaccines with the drug Keytruda to target skin cancer tumors after initial clinical trial success.

FTMQ Health, written by our newsroom0 views

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Picture: STAT News

Merck and Moderna are advancing efforts to pair the immunotherapy drug Keytruda with personalized messenger RNA vaccines to target cancer tumors, STAT News and Nacionale reported. Company executives Stephen Hoge and Dean Li discussed the joint project at the STAT Summit on Thursday. [1][3]

The clinical trials target patients with melanoma, a form of skin cancer that frequently recurs following surgery. According to STAT News, patient Gary Keblish entered a trial for the personalized vaccine after receiving a melanoma diagnosis and tumor surgery in 2019. Keblish reported that he remains healthy and continues to work as a public school teacher. [1]

Merck is an American multinational pharmaceutical firm headquartered in Rahway, New Jersey. Moderna was established in 2010 to create therapeutics based on modified messenger RNA technology. [5][7]

The drugmakers are exploring further applications for the therapeutic platform following early clinical success. Udreview reported that academic professors are also explaining the underlying mechanisms of these new cancer treatments. [1][3][4]

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In short

  • Merck and Moderna are combining Keytruda with personalized mRNA vaccines to treat cancer tumors.
  • The ongoing trial targets patients diagnosed with melanoma following surgical tumor removal.
  • Merck is based in Rahway, New Jersey, and Moderna was founded in 2010 to develop mRNA therapies.

Sources

Every paragraph above points to the numbered items it rests on. Read the originals here.

  1. [1]Merck and Moderna have ‘lot of exploring to do’ after initial cancer vaccine successSTAT News, 6h ago (the report this story comes from)
  2. [2]Merck and Moderna have ‘lot of exploring to do’ after initial cancer vaccine successSTAT, 6h ago
  3. [3]Merck and Moderna Advance Cancer Vaccine Following Initial SuccessNacionale, 4h ago
  4. [4]Professors explain Merck and Moderna’s new cancer vaccinesUdreview, 1d ago

Background

  1. [5]Merck & Co. on Wikipedia
  2. [6]COVID-19 vaccine on Wikipedia
  3. [7]Moderna on Grokipedia

Our newsroom writes these reports with the help of software, from the 7 sources listed and nothing else, and checks them against those sources. Facts can still be wrong or move on; the originals are the record. Spotted a mistake? Write to daniel@monsterkong.com.

Earlier reports of ours on the same people and subjects.

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