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Common airway bacterium helps mice lungs fight pneumonia in study

Exposure to a common mouth bacterium helped train lung immune cells in mice to defend against bacterial pneumonia, research shows.

FTMQ Health, written by our newsroom0 views

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Picture: Medical Xpress

A bacterium commonly found in human airways and mouths may assist the lungs in defending against pneumonia, Medical Xpress reported. The research was conducted by scientists at the University of Colorado Anschutz and published in the Proceedings of the National Academy of Sciences. [1]

Researchers found that exposure to Prevotella melaninogenica altered the behavior of immune cells inside the lungs of mice. The bacterium is typically present in healthy human airways. [1]

When the mice were subsequently exposed to Streptococcus pneumoniae, their immune responses were better prepared to fight the infection. Streptococcus pneumoniae is recognized as a leading cause of bacterial pneumonia. [1]

Bacteria are single-celled microorganisms present in almost all environments on Earth, including air, soil, and biological organisms. The findings highlight how resident microbes inside the body can interact with the immune system to offer protection against harmful pathogens. [1][2]

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In short

  • Prevotella melaninogenica is a common bacterium found in healthy human airways and mouths.
  • Researchers at the University of Colorado Anschutz tested the bacterium on immune cells in mice.
  • Prior exposure to the bacterium helped protect mice when later exposed to Streptococcus pneumoniae.
  • Streptococcus pneumoniae is a primary cause of bacterial pneumonia.

Sources

Every paragraph above points to the numbered items it rests on. Read the originals here.

  1. [1]Common airway bacterium may help prepare lungs to fight pneumoniaMedical Xpress, 3h ago (the report this story comes from)

Background

  1. [2]Bacteria on Wikipedia
  2. [3]Common on Grokipedia

Our newsroom writes these reports with the help of software, from the 3 sources listed and nothing else, and checks them against those sources. Facts can still be wrong or move on; the originals are the record. Spotted a mistake? Write to daniel@monsterkong.com.

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